Bose Krishnamachari has exhibited in several solo and group exhibitions including 'Bombay Maximum City’, ‘Lille 3000’, Lille, curated by Caroline Naphegyi (2006), ‘The Shape That Is’, Jendela and Concourse, Esplanade, Singapore (2006), Indian Art at the Swarovski ‘Crystal World, Innsbruck, Austria (2007), ‘Gateway Bombay’ at the Peabody Essex Museum (2007), India Art Now: Spazio Oberdan, Milan (2007), ‘Indian Highway’ at the Serpentine Gallery (2009), the Astrup Fearnley Museum, Norway (2009), the Herning Museum of Contemporary Art, Denmark (2010), the Lyon Contemporary Art Museum, the Fondazione MAXXI, Rome ()2011, and the ARTZUID Amsterdam-2011. His curatorial projects include the seminal exhibition ‘The Bombay Boys’, New Delhi-2004, ‘Double‐Enders,’ A travelling show - Mumbai, New Delhi, Bangalore and Kochi-2005, "AF-FAIR," 1X1 Contemporary and 1X1 Gallery, Dubai-2008, guest curator at the Indian pavilion of ARCO‐Madrid-2009, and the travelling project, LaVA (Laboratory of Audio Visual Arts)-2007-2011. In 2009, Krishnamachari created Gallery BMB in South Mumbai with a vision to bring the best national and international art to India.
He was Artistic Director and Co-Curator of India’s first Biennale – The Kochi-Muziris Biennale 2012, Director of Kochi-Muziris Biennale 2014, 2016 and 2018, and is President of the Kochi Biennale Foundation. Bose Krishnamachari curated For an Image, Faster than Light, first edition of the Yinchuan Biennale in Yinchuan, MOCA, Chairman, China which showed the work of 73 artists from 33 countries in the Museum of Contemporary Art, Yinchuan. He is also a Board Member of the International Biennale Association.
Most recently, he opened his solo show, ‘The Mirror Sees Best in the Dark’ at Emami Art Gallery, Kolkata.